Triple Negative Breast Cancer
Did you know that TNBC accounts for approximately 15% of all breast cancers?
60-90% of the tumors in BRCA 1 carries are triple negative.
In a recent study, 18% of unselected patients with triple negative breast cancer had BRCA1/2 mutations.
NCCN Testing criteria includes HBOC syndrome testing for patients with TNBC under age 60.
Source of Information: Myriad Genetics, Inc.
Male Breast Cancer
Multiple professional society guidelines state that a personal or family history of male breast cancer is a criterion for HBOC testing.
1 in 7 Ashkenazi Jewish males diagnosed with breast cancer will have a BRCA mutation. 1 in 14 non-Ashkenazi Jewish males diagnosed with breast cancer will have a BRCA mutation.
Men with BRCA mutations are at increased risk for several types of cancer. These include breast cancer, prostate cancer, pancreatic cancer, and melanoma.
Multiple professional society guidelines state that a personal or family history of epithelial ovarian cancer is a criterion for HBOC testing.
55% of ovarian cancer patients at a major US cancer center were not aware of hereditary cancer testing.
89% of patients were willing to be tested if it would affect their therapy and 87% would be tested to benefit their family.
Source: Myraid Lab
Most insurance companies cover testing for patients with a history of the cancer listed. It is important to find out your personal and family history forms to see if you qualify for testing.